Structural Biology - Antibody Engineering - Protein Science
Brooks Lab - Antibody Biotechnology
Antibodies are immune system proteins which help our bodies fight infection. The ability to rapidly produce antibodies in the lab has allowed scientists to generate antibodies that bind and destroy not only infections, but also cancer cells. This approach to treatment, called immunotherapy has revolutionized medicine.
The Brooks lab raims to understand the molecular basis for how antibodies bind their targets. We primarily use an approach called X-ray crystallography, which allows atomic resolution analysis of antibody structure. We use this information to inform antibody engineering and design of next-generation antibody drugs.
For information on specific research projects see our research page
Students and Training
The Brooks lab has research opportunities for both graduate students (MS Chemistry, Biology, Biotechnology) and undergraduates (Chemistry, Biochemistry, Biology). Alumni from my lab have obtained positions in biotechnology companies, food safety, and in education.
Research students will learn a variety of techniques including cell culture, protein purification, molecular biology and X-ray crystallography. Students frequently present their research at national and International meetings and have been co-authors on many publications.
Contact Dr. Brooks if you are interested in antibody research in a dynamic and challenging environment.