Structural Biology - Antibody Engineering - Protein Science
Brooks Lab - Antibody Biotechnology
Antibodies are immune system proteins which help our bodies fight infection. The ability to rapidly produce antibodies in the lab has allowed scientists to generate antibodies that bind and destroy not only infections, but also cancer cells. This approach to treatment, called immunotherapy has revolutionized medicine.
The Brooks lab raims to understand the molecular basis for how antibodies bind their targets. We primarily use an approach called X-ray crystallography, which allows atomic resolution analysis of antibody structure. We use this information to inform antibody engineering and design of next-generation antibody drugs.
For information on specific research projects see our research page